Cabergoline

Cabergoline belongs to the class of medications called dopamine mimetics. It is able to interact with dopamine-type receptors located in the pituitary gland. This leads to a significant suppression of the production of the hormone prolactin. In medicine, the agent is used during the treatment of a disease such as hyperprolactinemia. Cabergoline is also actively used in bodybuilding.

In addition, cabergoline can be effective for menstrual irregularities, galactorrhea, low sex drive, impotence. It is also used to prevent the suppression of the lactation process. In addition to the ability to interact with dopamine-type receptors, Cabergoline is a weak agonist of alpha-1 and alpha-2 adrenergic receptors.

The drug is a selective agonist of dopamine-type receptors and at the same time works quite specifically. It should be noted its high similarity with the D2 receptors, but the drug interacts weakly with adrenergic (alpha-1 and alpha-2) and serotonin (5-HT1, 5-HT2) receptors.

For therapeutic purposes, this agent is used in the treatment of hyperprolactinemia, hypersecretion of the hormone prolactin by the pituitary gland, as well as in Parkinson's disease. The drug has a high ability to inhibit prolactin synthesis and it is for this reason that cabergoline is very popular in bodybuilding. At the same time, the agent interacts with D2 receptors. Thus, dopamine becomes negative feedback for prolactin release.

We have already said that an important feature of the drug is its inability to influence the processes of synthesis of other hormonal substances synthesized by the cellular structures of the pituitary gland - corticotropin, growth hormone, luteinizing, and thyroid stimulating hormones.